StartImmunsystemWas ist Diabetes mellitus Typ 1?

    Was ist Diabetes mellitus Typ 1?

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    Type 1 Diabetes Mellitus is a serious illness that could change rapidly. Type 1 Diabetes develops most commonly in children, teens, and young adults. The cause of this problem is an immune or viral assault on the pancreas, specifically upon the insulin-producing centres of the pancreas, which can be known as the Islets of Langerhans.

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    The Islets of Langerhans are miniature “nests” of cells that “feel” the blood levels of sugar and synthesize and secrete insulin in response. These Islets can be destroyed, however, by viral assault or from immune attack, where one’s own immune system produces antibodies that specifically attach and destroy the Islet cells.

    The immune attack badly knocks out insulin production, and the end result is persistent elevation in blood sugar concentrations which can be severe. The change in the pancreas’ ability to detect glucose levels and secrete insulin may differ from mild to moderate to severe. It is dependent upon the intensity of the immune attack. If moderate or severe, blood sugar concentrations may rise from the standard variety of 70-100 mg/dL to values over 500 mg/dL or even over 1000 mg/dL.

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    Glucose levels

    These very substantial levels of glucose lead to rapid dehydration, diminished alertness or even coma, and decreasing blood pressures to the degree of true shock. Hence, Type 1 Diabetes Mellitus is termed”brittle,” since it can result in major sickness so quickly. Why an individual undergoes immune attack or viral attack on the pancreas isn’t fully understood. A genetic susceptibility might be one reason.

    Exposure to a particular virus might be another reason, but investigators at the cause of Diabetes aren’t certain. Blood testing may reveal antibodies to the Islet Cells of Langerhans. These antibodies are known as “Anti Islet Cell Antibodies,” and this blood test can be carried out in hospital labs and national testing centers. Detecting Anti Islet Cell Antibodies is an important evaluation for a young person who develops elevated blood sugar concentrations, since this result controls rapid management.


    Insulin levels can be measured also and then a strategy for insulin prescribing, by injection, can be developed and tailored. With inadequate insulin production, blood sugar concentrations increases and swing radically, and insulin replacement is the crucial prescription for the young person confirmed to have Type 1 Diabetes Mellitus. Brittle is an essential qualifier for Type 1 Diabetes Mellitus, for once insulin replacement is prescribed for everyday injection, a day or 2 days of insulin injection will probably cause rapid deterioration of balance, with rapidly increasing glucose levels, rapid dehydration, psychological change, and deterioration to a diabetes crisis.

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    Severe illness and life threatening ketoacidosis can and will probably evolve. More about this is written in companion articles. All household members and close friends of someone known to have Type 1 Diabetes Mellitus has to be educated, aware, and alert to this delicate nature of Type 1 Diabetes Mellitus. Caring reminders and helpful advice to the affected individual to inject their insulin schedule, without failure, and also to adhere to the diabetic diet with precision will tremendously help to control this fragile disease.



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