The principle behind acne is well known by scientists but physicians continually deal with outcome of acne rather than the cause. Acne is fundamentally the result of a change in hormonal balance. At times of our lives our well known hormones can fluctuate away from the standard as well as the skin becomes’aware’ and sensitive to a hormone called DHT that it generally pays no heed .
Through puberty and adolescent years to approx. DHT sensitivity causes fatty acid imbalance in the skin that’s quite tough to replace orally as very little reaches your skin. As a result of this imbalance, the oil producing glands in the skin react by increasing oil production. Typically the skin begins to thicken (known as keratinisation) and skin shedding slows (called hyper cornification).
Oftentimes, (not all) the cell linings of the inner walls of the hair follicle where the oil produced by sebaceous glands comes from, thickens and hence the tube narrows in diameter, which means you’ve got more oil trying to escape a narrower tube. Also skin tissues become stickier and clump together, so the pace at which we naturally discard skin slows down, causing the buildup of surface skin debris that in combination with surplus oil forms a’plug’ in the duct opening that’s closing because of skin thickening. This creates a blockage. So far you do not have acne; you don’t have comedones or pimples.
However skin bacteria that prefer a low oxygen environment such as p.acnes develop beneath the’plug’ in this oxygen deficient environment and begin to digest the plug that generates by-products, which trigger inflammation. Bacteria are therefore not the principal cause of acne but their reaction to the changes in the skin which contributes to spots. So in the event you’re able to control the inherent sensitivity then the bacteria won’t be such an issue. Also you have to control the p.acnes germs without attacking the healthful skin germs like Staph epidermidis that may induce resistant bacteria and might well be a primary cause of hospital super bug resistance.
The by-products generated cause inflammation and damage to surrounding tissues causing a place, and now you’ve got a pustular acne lesion or ‘yellow head’. The skin returns to normal once hormonal levels balance out and the skin becomes ‘unaware’ of DHT and acne free. However in a considerable number of people they’re left with a residual community sensitivity to DHT, in spite of a normal hormonal balance, which may result in long term acne and spots as well as the infamous T Zone.